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The efficiency of damage recognition and excision correlate with duplex destabilization induced by acetylaminofluorene adducts in human nucleotide excision repair

Nucleotide excision repair (NER) removes lesions caused by environmental mutagens or UV light from DNA. A hallmark of NER is the extraordinarily wide substrate specificity, raising the question of how one set of proteins is able to recognize structurally diverse lesions. Two key features of good NER...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Yeo, Jung-Eun, Khoo, Andy, Fagbemi, Adebanke F., Schärer, Orlando D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502718/
https://ncbi.nlm.nih.gov/pubmed/23088760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx3003033
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