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α(5)β(1)-Integrin controls ebolavirus entry by regulating endosomal cathepsins

Integrins are involved in the binding and internalization of both enveloped and nonenveloped viruses. By using 3 distinct cell systems—CHO cells lacking expression of α(5)β(1)-integrin, HeLa cells treated with siRNA to α(5)-integrin, and mouse β(1)-integrin knockout fibroblasts, we show that α(5)β(1...

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Detalhes bibliográficos
Main Authors: Schornberg, Kathryn L., Shoemaker, Charles J., Dube, Derek, Abshire, Michelle Y., Delos, Sue E., Bouton, Amy H., White, Judith M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683081/
https://ncbi.nlm.nih.gov/pubmed/19416892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807578106
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