Prolonged Exposure to Insulin Suppresses Mitochondrial Production in Primary Hepatocytes

Insulin is the central regulator of metabolism and is necessary for storing energy as fat efficiently. Mitochondria are primary sites of energy consumption of most cells. Increased plasma insulin level and mitochondrial dysfunction are features of insulin resistance. The exact role of insulin in reg...

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Hlavní autoři: Liu, Hui-Yu, Yehuda-Shnaidman, Einav, Hong, Tao, Han, Jianmin, Pi, Jingbo, Liu, Zhenqi, Cao, Wenhong
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
Metabolism and Bioenergetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682857/
https://ncbi.nlm.nih.gov/pubmed/19336408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807992200
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