A Correspondence Between Solution-State Dynamics of an Individual Protein and the Sequence and Conformational Diversity of its Family

Conformational ensembles are increasingly recognized as a useful representation to describe fundamental relationships between protein structure, dynamics and function. Here we present an ensemble of ubiquitin in solution that is created by sampling conformational space without experimental informati...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Friedland, Gregory D., Lakomek, Nils-Alexander, Griesinger, Christian, Meiler, Jens, Kortemme, Tanja
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2009
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682763/
https://ncbi.nlm.nih.gov/pubmed/19478996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000393
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