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Development of Selective Axonopathy in Adult Sensory Neurons Isolated From Diabetic Rats: Role of Glucose-Induced Oxidative Stress

OBJECTIVE: Reactive oxygen species (ROS) are pro-oxidant factors in distal neurodegeneration in diabetes. We tested the hypothesis that sensory neurons exposed to type 1 diabetes would exhibit enhanced ROS and oxidative stress and determined whether this stress was associated with abnormal axon outg...

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Detalhes bibliográficos
Main Authors: Zherebitskaya, Elena, Akude, Eli, Smith, Darrell R., Fernyhough, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682687/
https://ncbi.nlm.nih.gov/pubmed/19252136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0034
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