FoxO1 Haploinsufficiency Protects Against High-Fat Diet–Induced Insulin Resistance With Enhanced Peroxisome Proliferator–Activated Receptor γ Activation in Adipose Tissue

OBJECTIVE: Forkhead box O (FoxO) transcription factors represent evolutionarily conserved targets of insulin signaling, regulating metabolism and cellular differentiation in response to changes in nutrient availability. Although the FoxO1 isoform is known to play a key role in adipogenesis, its phys...

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Detalhes bibliográficos
Main Authors: Kim, Jane J., Li, Pingping, Huntley, Jessica, Chang, Jeffrey P., Arden, Karen C., Olefsky, Jerrold M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682681/
https://ncbi.nlm.nih.gov/pubmed/19289458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-1001
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