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Adaptive β-Cell Proliferation Is Severely Restricted With Advanced Age

OBJECTIVE: Regeneration of the insulin-secreting β-cells is a fundamental research goal that could benefit patients with either type 1 or type 2 diabetes. β-Cell proliferation can be acutely stimulated by a variety of stimuli in young rodents. However, it is unknown whether this adaptive β-cell rege...

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Autori principali: Rankin, Matthew M., Kushner, Jake A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682671/
https://ncbi.nlm.nih.gov/pubmed/19265026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-1198
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