MinK-dependent internalization of the I(Ks) potassium channel

AIMS: KCNQ1–MinK potassium channel complexes (4α:2β stoichiometry) generate I(Ks), the slowly activating human cardiac ventricular repolarization current. The MinK ancillary subunit slows KCNQ1 activation, eliminates its inactivation, and increases its unitary conductance. However, KCNQ1 transcripts...

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Bibliographic Details
Main Authors: Xu, Xianghua, Kanda, Vikram A., Choi, Eun, Panaghie, Gianina, Roepke, Torsten K., Gaeta, Stephen A., Christini, David J., Lerner, Daniel J., Abbott, Geoffrey W.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2009
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682613/
https://ncbi.nlm.nih.gov/pubmed/19202166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvp047
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