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The Role of S4 Charges in Voltage-dependent and Voltage-independent KCNQ1 Potassium Channel Complexes

Voltage-gated potassium (Kv) channels extend their functional repertoire by coassembling with MinK-related peptides (MiRPs). MinK slows the activation of channels formed with KCNQ1 α subunits to generate the voltage-dependent I(Ks) channel in human heart; MiRP1 and MiRP2 remove the voltage dependenc...

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Autors principals: Panaghie, Gianina, Abbott, Geoffrey W.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2154355/
https://ncbi.nlm.nih.gov/pubmed/17227916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200609612
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