Integrating shotgun proteomics and mRNA expression data to improve protein identification

Motivation: Tandem mass spectrometry (MS/MS) offers fast and reliable characterization of complex protein mixtures, but suffers from low sensitivity in protein identification. In a typical shotgun proteomics experiment, it is assumed that all proteins are equally likely to be present. However, there...

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Hlavní autoři: Ramakrishnan, Smriti R., Vogel, Christine, Prince, John T., Li, Zhihua, Penalva, Luiz O., Myers, Margaret, Marcotte, Edward M., Miranker, Daniel P., Wang, Rong
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
Original Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682515/
https://ncbi.nlm.nih.gov/pubmed/19318424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp168
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