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Mining gene functional networks to improve mass-spectrometry-based protein identification

Motivation: High-throughput protein identification experiments based on tandem mass spectrometry (MS/MS) often suffer from low sensitivity and low-confidence protein identifications. In a typical shotgun proteomics experiment, it is assumed that all proteins are equally likely to be present. However...

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Detalhes bibliográficos
Main Authors: Ramakrishnan, Smriti R., Vogel, Christine, Kwon, Taejoon, Penalva, Luiz O., Marcotte, Edward M., Miranker, Daniel P.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773251/
https://ncbi.nlm.nih.gov/pubmed/19633097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp461
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