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Integrating shotgun proteomics and mRNA expression data to improve protein identification
Motivation: Tandem mass spectrometry (MS/MS) offers fast and reliable characterization of complex protein mixtures, but suffers from low sensitivity in protein identification. In a typical shotgun proteomics experiment, it is assumed that all proteins are equally likely to be present. However, there...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Oxford University Press
2009
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2682515/ https://ncbi.nlm.nih.gov/pubmed/19318424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp168 |
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