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Exploring causality via identification of SNPs or haplotypes responsible for a linkage signal

In a small chromosomal region, a number of polymorphisms may be both linked to and associated with a disease. Distinguishing the potential causal sites from those indirectly associated due to linkage disequilibrium (LD) with a causal site is an important problem. This problem may be approached by de...

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Autors principals: Biernacka, Joanna M, Cordell, Heather J
Format: Artigo
Idioma:Inglês
Publicat: Wiley Subscription Services, Inc., A Wiley Company 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682330/
https://ncbi.nlm.nih.gov/pubmed/17508343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20236
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