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UV as an amplifier rather than inducer of NF-κB activity
Inflammatory activation of NF-κB involves the stimulus-induced degradation of the NF-κB-bound inhibitor, IκB, via the IκB kinase (IKK). In response to UV irradiation, however, the mechanism and function of NF-κB activation remain unclear. Using a combined biochemical, genetic, and computational mode...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2682114/ https://ncbi.nlm.nih.gov/pubmed/18538661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.03.017 |
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