Mutations in gp120 Contribute to the Resistance of Human Immunodeficiency Virus Type 1 to Membrane-Anchored C-Peptide maC46

Binding of the human immunodeficiency virus (HIV) envelope glycoprotein (Env) to the cellular CD4 receptor and a chemokine coreceptor initiates a series of conformational changes in the Env subunits gp120 and gp41. Eventually, the trimeric gp41 folds into a six-helix bundle, thereby inducing fusion...

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Détails bibliographiques
Auteurs principaux: Hermann, Felix G., Egerer, Lisa, Brauer, Frances, Gerum, Christian, Schwalbe, Harald, Dietrich, Ursula, von Laer, Dorothee
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2009
Sujets:
Vaccines and Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682112/
https://ncbi.nlm.nih.gov/pubmed/19279116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00666-08
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