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Intramolecular Disulfide Bonds of the Prolactin Receptor Short Form Are Required for Its Inhibitory Action on the Function of the Long Form of the Receptor

The short form (S1b) of the prolactin receptor (PRLR) silences prolactin-induced activation of gene transcription by the PRLR long form (LF). The functional and structural contributions of two intramolecular disulfide (S-S) bonds within the extracellular subdomain 1 (D1) of S1b to its inhibitory fun...

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Detalhes bibliográficos
Main Authors: Xie, Y.-L., Hassan, S. A., Qazi, A. M., Tsai-Morris, C. H., Dufau, M. L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682051/
https://ncbi.nlm.nih.gov/pubmed/19273600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01716-08
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