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Impact of subdomain D1 of the short form S1b of the human prolactin receptor on its inhibitory action on the function of the long form of the receptor induced by prolactin
BACKGROUND: Long-form (LF) homodimers of the human prolactin receptor (PRLR) mediate prolactin’s diverse actions. Short form S1b inhibits the LF function through heterodimerization. Reduced S1b/LF-ratio in breast cancer could contribute to tumor development/progression. Current work defines the stru...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4061154/ https://ncbi.nlm.nih.gov/pubmed/24735798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2014.04.006 |
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