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p53 Suppresses Src-Induced Podosome and Rosette Formation and Cellular Invasiveness through the Upregulation of Caldesmon

The tumor-suppressive role of p53 at the level of tumor initiation is well documented. It has also been shown previously that p53 acts against tumor progression/metastasis. However, its role in modulating cell migration and invasion leading to metastasis is poorly understood. In this study, using va...

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Bibliografiske detaljer
Main Authors: Mukhopadhyay, Utpal K., Eves, Robert, Jia, Lilly, Mooney, Patrick, Mak, Alan S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682007/
https://ncbi.nlm.nih.gov/pubmed/19349302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01816-08
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