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Doubles Game: Src-Stat3 versus p53-PTEN in Cellular Migration and Invasion

We have recently shown that Src induces the formation of podosomes and cell invasion by suppressing endogenous p53, while enhanced p53 strongly represses the Src-induced invasive phenotype. However, the mechanism by which Src and p53 play antagonistic roles in cell invasion is unknown. Here we show...

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Bibliographic Details
Main Authors: Mukhopadhyay, Utpal K., Mooney, Patrick, Jia, Lilly, Eves, Robert, Raptis, Leda, Mak, Alan S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953057/
https://ncbi.nlm.nih.gov/pubmed/20733006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00004-10
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