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Effect of Ribavirin on the Mutation Rate and Spectrum of Hepatitis C Virus In Vivo
Their extremely error-prone replication makes RNA viruses targets for lethal mutagenesis. In the case of hepatitis C virus (HCV), the standard treatment includes ribavirin, a base analog with an in vitro mutagenic effect, but the in vivo mode of action of ribavirin remains poorly understood. Here, w...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2681971/ https://ncbi.nlm.nih.gov/pubmed/19321623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00201-09 |
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