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Validating viral quasispecies with digital organisms: a re-examination of the critical mutation rate

BACKGROUND: In this report we re-examine some recent experiments with digital organisms to test some predictions of quasispecies theory. These experiments revealed that under high mutation rates populations of less fit organisms previously adapted to such high mutation rates were able to outcompete...

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Detalhes bibliográficos
Main Authors: Comas, Iñaki, Moya, Andrés, González-Candelas, Fernando
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC546199/
https://ncbi.nlm.nih.gov/pubmed/15651995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-5-5
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