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Arginine Methylation of the ICP27 RGG Box Regulates ICP27 Export and Is Required for Efficient Herpes Simplex Virus 1 Replication

The herpes simplex virus 1 (HSV-1) multifunctional regulatory protein ICP27 shuttles between the nucleus and cytoplasm in its role as a viral mRNA export factor. Arginine methylation on glycine- and arginine-rich motifs has been shown to regulate protein export. ICP27 contains an RGG box and has bee...

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Библиографические подробности
Главные авторы: Souki, Stuart K., Gershon, Paul D., Sandri-Goldin, Rozanne M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681963/
https://ncbi.nlm.nih.gov/pubmed/19321610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00238-09
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