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Pyruvate Kinase-Deficient Escherichia coli Exhibits Increased Plasmid Copy Number and Cyclic AMP Levels

Previously established consequences of abolishing pyruvate kinase (Pyk) activity in Escherichia coli during aerobic growth on glucose include reduced acetate production, elevated hexose monophosphate (HMP) pathway flux, elevated phosphoenolpyruvate carboxylase (Ppc) flux, and an increased ratio of p...

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Главные авторы: Cunningham, Drew S., Liu, Zhu, Domagalski, Nathan, Koepsel, Richard R., Ataai, Mohammad M., Domach, Michael M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681811/
https://ncbi.nlm.nih.gov/pubmed/19251844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01422-08
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