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Engineering of Bacillus subtilis for Enhanced Total Synthesis of Folic Acid

We investigated whether the yield of the B vitamin folic acid could be elevated in Bacillus subtilis. Strategies for increasing the folic acid yield were investigated by employing computer-aided flux analysis and mutation. Controlling the activity of the enzyme pyruvate kinase by placing it under in...

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Detalhes bibliográficos
Main Authors: Zhu, T., Pan, Z., Domagalski, N., Koepsel, R., Ataai, M. M., Domach, M. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1287646/
https://ncbi.nlm.nih.gov/pubmed/16269750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.71.11.7122-7129.2005
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