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Engineering of Bacillus subtilis for Enhanced Total Synthesis of Folic Acid
We investigated whether the yield of the B vitamin folic acid could be elevated in Bacillus subtilis. Strategies for increasing the folic acid yield were investigated by employing computer-aided flux analysis and mutation. Controlling the activity of the enzyme pyruvate kinase by placing it under in...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1287646/ https://ncbi.nlm.nih.gov/pubmed/16269750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.71.11.7122-7129.2005 |
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