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Factors affecting plasmid production in Escherichia coli from a resource allocation standpoint

BACKGROUND: Plasmids are being reconsidered as viable vector alternatives to viruses for gene therapies and vaccines because they are safer, non-toxic, and simpler to produce. Accordingly, there has been renewed interest in the production of plasmid DNA itself as the therapeutic end-product of a bio...

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Detalhes bibliográficos
Main Authors: Cunningham, Drew S, Koepsel, Richard R, Ataai, Mohammad M, Domach, Michael M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702362/
https://ncbi.nlm.nih.gov/pubmed/19463175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-8-27
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