Development of Non-Antibiotic-Resistant, Chromosomally Based, Constitutive and Inducible Expression Systems for aroA-Attenuated Salmonella enterica Serovar Typhimurium

Live-vaccine delivery systems expressing two model antigens from Mycoplasma hyopneumoniae, F2(P97) (Adh) and NrdF, were constructed using Salmonella enterica serovar Typhimurium aroA (STM-1), and immunogenicity in mice was evaluated. Recombinant plasmid-based expression (PBE) and chromosomally based...

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Autori principali: Matic, Jake N., Terry, Tamsin D., Van Bockel, David, Maddocks, Tracy, Tinworth, David, Jennings, Michael P., Djordjevic, Steven P., Walker, Mark J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2009
Soggetti:
Microbial Immunity and Vaccines
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681777/
https://ncbi.nlm.nih.gov/pubmed/19223478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01301-08
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