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First Streptococcus pyogenes Signature-Tagged Mutagenesis Screen Identifies Novel Virulence Determinants

The virulence of bacterial pathogens is a complex process that requires the dynamic expression of many genes for the pathogens to invade and circumvent host defenses, as well as to proliferate in vivo. In this study, we employed a large-scale screen, signature-tagged mutagenesis (STM), to identify S...

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書目詳細資料
Main Authors: Kizy, Anne E., Neely, Melody N.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681771/
https://ncbi.nlm.nih.gov/pubmed/19223485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01306-08
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