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First Streptococcus pyogenes Signature-Tagged Mutagenesis Screen Identifies Novel Virulence Determinants

The virulence of bacterial pathogens is a complex process that requires the dynamic expression of many genes for the pathogens to invade and circumvent host defenses, as well as to proliferate in vivo. In this study, we employed a large-scale screen, signature-tagged mutagenesis (STM), to identify S...

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Detalhes bibliográficos
Main Authors: Kizy, Anne E., Neely, Melody N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681771/
https://ncbi.nlm.nih.gov/pubmed/19223485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01306-08
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