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Signature-Tagged Mutagenesis of Pasteurella multocida Identifies Mutants Displaying Differential Virulence Characteristics in Mice and Chickens

Pasteurella multocida is the causative agent of fowl cholera in birds. Signature-tagged mutagenesis (STM) was used to identify potential virulence factors in a mouse septicemia disease model and a chicken fowl cholera model. A library of P. multocida mutants was constructed with a modified Tn916 and...

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Autors principals: Harper, Marina, Boyce, John D., Wilkie, Ian W., Adler, Ben
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC187344/
https://ncbi.nlm.nih.gov/pubmed/12933901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.9.5440-5446.2003
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