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Combination Therapy of Advanced Invasive Pulmonary Aspergillosis in Transiently Neutropenic Rats Using Human Pharmacokinetic Equivalent Doses of Voriconazole and Anidulafungin

At present, voriconazole (VOR) is the drug of first choice for treating invasive pulmonary aspergillosis (IPA). However, particularly in advanced stages of disease and in the severely immunocompromised host, the mortality remains substantial. The combination of VOR with an echinocandin may improve t...

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書誌詳細
主要な著者: van de Sande, Wendy W. J., Mathot, Ron A. A., ten Kate, Marian T., van Vianen, Wim, Tavakol, Mehri, Rijnders, Bart J. A., Bakker-Woudenberg, Irma A. J. M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681552/
https://ncbi.nlm.nih.gov/pubmed/19237647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01556-08
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