The role of LMNA in adipose: a novel mouse model of lipodystrophy based on the Dunnigan-type familial partial lipodystrophy mutation

We investigated the role of LMNA in adipose tissue by developing a novel mouse model of lipodystrophy. Transgenic mice were generated that express the LMNA mutation that causes familial partial lipodystrophy of the Dunnigan type (FPLD2). The phenotype observed in FPLD-transgenic mice resembles many...

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Hlavní autoři: Wojtanik, Kari M., Edgemon, Keith, Viswanadha, Srikant, Lindsey, Brigette, Haluzik, Martin, Chen, Weiping, Poy, George, Reitman, Marc, Londos, Constantine
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681389/
https://ncbi.nlm.nih.gov/pubmed/19201734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800491-JLR200
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