Reverse genetic analysis of Caenorhabditis elegans presenilins reveals redundant but unequal roles for sel-12 and hop-1 in Notch-pathway signaling

Eitemau Tebyg

• HOP-1, a Caenorhabditis elegans presenilin, appears to be functionally redundant with SEL-12 presenilin and to facilitate LIN-12 and GLP-1 signaling
  gan: Li, Xiajun, et al.
  Cyhoeddwyd: (1997)
• Loss of spr-5 bypasses the requirement for the C.elegans presenilin sel-12 by derepressing hop-1
  gan: Eimer, S., et al.
  Cyhoeddwyd: (2002)
• HOP-1 Presenilin Deficiency Causes a Late-Onset Notch Signaling Phenotype That Affects Adult Germline Function in Caenorhabditis elegans
  gan: Agarwal, Ipsita, et al.
  Cyhoeddwyd: (2018)
• High-Throughput Isolation of Caenorhabditis elegans Deletion Mutants
  gan: Liu, Leo X., et al.
  Cyhoeddwyd: (1999)
• Evidence for functional and physical association between Caenorhabditis elegans SEL-10, a Cdc4p-related protein, and SEL-12 presenilin
  gan: Wu, Guangyu, et al.
  Cyhoeddwyd: (1998)