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Loss of Rap1GAP in Papillary Thyroid Cancer

Context: Rap1 GTPase-activating protein (GAP) regulates the activity of Rap1, a putative oncogene. We previously reported Rap1GAP was highly expressed in normal human thyroid cells and decreased in five papillary thyroid carcinomas (PTCs). Objectives: To confirm the significance of these findings, w...

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Autori principali: Nellore, Anoma, Paziana, Karolina, Ma, Changqing, Tsygankova, Oxana M., Wang, Yan, Puttaswamy, Kanchan, Iqbal, Ammarah U., Franks, Susanna R., Lv, Yu, Troxel, Andrea B., Feldman, Michael D., Meinkoth, Judy L., Brose, Marcia S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Endocrine Society 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681278/
https://ncbi.nlm.nih.gov/pubmed/19066305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2008-1042
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