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Hematopoietic stem cells do not depend on N-cadherin to regulate their maintenance
According to the “osteoblastic niche” model, hematopoietic stem cells (HSCs) are maintained by N-cadherin-mediated homophilic adhesion to osteoblasts at the bone marrow endosteum. In contrast to this model, we cannot detect N-cadherin expression by HSCs and most HSCs do not localize to the endosteal...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2009
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2681089/ https://ncbi.nlm.nih.gov/pubmed/19119091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2008.10.005 |
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