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Genetic Engineering of a Modified Herpes Simplex Virus 1 Vaccine Vector

The herpes simplex virus 1 (HSV-1) d106 mutant virus is a multiple immediate-early gene deletion mutant virus that has been effective as an AIDS vaccine vector in rhesus macaques (Kaur et al. 2007. Virology 357: 199–214). Further analysis of this vector is needed to advance development into clinical...

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Bibliographic Details
Main Authors: Liu, XueQiao, Broberg, Eeva, Watanabe, Daisuke, Dudek, Timothy, DeLuca, Neal, Knipe, David M.
Format: Artigo
Language:Inglês
Published: 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680798/
https://ncbi.nlm.nih.gov/pubmed/19428888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.03.003
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