Herpes Simplex Virus 1 Has Multiple Mechanisms for Blocking Virus-Induced Interferon Production

In response to viral infection, host cells elicit a number of responses, including the expression of alpha/beta interferon (IFN-α/β). In these cells, IFN regulatory factor-3 (IRF-3) undergoes a sequence of posttranslational modifications that allow it to act as a potent transcriptional coactivator o...

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Bibliographic Details
Main Authors: Melroe, Gregory T., DeLuca, Neal A., Knipe, David M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC479070/
https://ncbi.nlm.nih.gov/pubmed/15280450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.16.8411-8420.2004
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