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Attenuation of CD8(+) T-Cell Function by CD4(+)CD25(+) Regulatory T Cells in B-Cell Non-Hodgkin's Lymphoma

The underlying mechanisms by which tumor cells are resistant to CTL-mediated apoptosis are not clear. Using a human model of B-cell non-Hodgkin's lymphoma (B-cell NHL), we show that intratumoral T(reg) cells inhibit the proliferation and granule production of activated autologous infiltrating C...

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Détails bibliographiques
Auteurs principaux: Yang, Zhi-Zhang, Novak, Anne J., Ziesmer, Steven C., Witzig, Thomas E., Ansell, Stephen M.
Format: Artigo
Langue:Inglês
Publié: 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680600/
https://ncbi.nlm.nih.gov/pubmed/17047079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-06-1822
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