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Intratumoral CD4(+)CD25(+) regulatory T-cell-mediated suppression of infiltrating CD4(+) T cells in B-cell non-Hodgkin lymphoma
Most non-Hodgkin lymphomas (NHLs) are of B-cell origin, but the tumor tissue can be variably infiltrated with T cells. In the present study, we have identified a subset of CD4(+)CD25(+) T cells with high levels of CTLA-4 and Foxp3 (intratumoral T(reg) cells) that are overrepresented in biopsy specim...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
© 2006 by The American Society of Hematology
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895773/ https://ncbi.nlm.nih.gov/pubmed/16403912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-08-3376 |
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