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Transplacental exposure to inorganic arsenic at a hepatocarcinogenic dose induces fetal gene expression changes in mice indicative of aberrant estrogen signaling and disrupted steroid metabolism

Exposure to inorganic arsenic in utero in C3H mice produces hepatocellular carcinoma in male offspring when they reach adulthood. To help define the molecular events associated with the fetal onset of arsenic hepatocarcinogenesis, pregnant C3H mice were given drinking water containing 0 (control) or...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Liu, Jie, Xie, Yaxiong, Cooper, Ryan, Ducharme, Danica M.K., Tennant, Raymond, Diwan, Bhalchandra A., Waalkes, Michael P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680420/
https://ncbi.nlm.nih.gov/pubmed/17350061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2007.01.018
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