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Fetal Onset of Aberrant Gene Expression Relevant to Pulmonary Carcinogenesis in Lung Adenocarcinoma Development Induced by In Utero Arsenic Exposure

Arsenic is a human pulmonary carcinogen. Our work indicates that in utero arsenic exposure in mice can induce or initiate lung cancer in female offspring. To define early molecular changes, pregnant C3H mice were given 85 ppm arsenic in drinking water from days 8 to 18 of gestation and expression of...

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Главные авторы: Shen, Jun, Liu, Jie, Xie, Yaxiong, Diwan, Bhalchandra A., Waalkes, Michael P.
Формат: Artigo
Язык:Inglês
Опубликовано: 2006
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692318/
https://ncbi.nlm.nih.gov/pubmed/17077188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfl151
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