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Renal, hepatic, pulmonary and adrenal tumors induced by prenatal inorganic arsenic followed by dimethylarsinic acid in adulthood in CD1 mice

Inorganic arsenic, an early life carcinogen in humans and mice, can initiate lesions promotable by other agents in later life. The biomethylation product of arsenic, dimethylarsinic acid (DMA), is a multi-site tumor promoter. Thus, pregnant CD1 mice were given drinking water (0 or 85 ppm arsenic) fr...

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Detalhes bibliográficos
Main Authors: Tokar, Erik J., Diwan, Bhalchandra A., Waalkes, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285471/
https://ncbi.nlm.nih.gov/pubmed/22230260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2011.12.016
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