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Early Life Inorganic Lead Exposure Induces Testicular Teratoma and Renal and Urinary Bladder Preneoplasia in Adult Metallothionein-Knockout Mice but Not in Wild Type Mice

Inorganic lead compounds are carcinogenic in animals and have carcinogenic potential in humans. In mice, lead (Pb) is a transplacental carcinogen in the kidney. Metallothionein (MT) is a metal-binding protein that can reduce the toxicity of various metals, including Pb, either by direct sequestratio...

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Detalhes bibliográficos
Main Authors: Tokar, Erik J., Diwan, Bhalchandra A., Waalkes, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951012/
https://ncbi.nlm.nih.gov/pubmed/20600549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2010.06.006
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