Bilirubin, formed by activation of heme oxygenase-2, protects neurons against oxidative stress injury

Heme oxygenase (HO) catalyzes the conversion of heme to carbon monoxide, iron, and biliverdin, which is immediately reduced to bilirubin (BR). Two HO active isozymes exist: HO1, an inducible heat shock protein, and HO2, which is constitutive and highly concentrated in neurons. We demonstrate a neuro...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Doré, Sylvain, Takahashi, Masaaki, Ferris, Christopher D., Hester, Lynda D., Guastella, Daniel, Snyder, Solomon H.
פורמט: Artigo
שפה:Inglês
יצא לאור: The National Academy of Sciences 1999
נושאים:
Biological Sciences
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC26804/
https://ncbi.nlm.nih.gov/pubmed/10051662
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