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Gfi1 regulates miR-21 and miR-196b to control myelopoiesis

The zinc finger protein growth factor independent-1 (Gfi1) is a transcriptional repressor that is critically required for normal granulocytic differentiation. GFI1 loss-of-function mutations are found in some patients with severe congenital neutropenia (SCN). The SCN-associated GFI1-mutant proteins...

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Sonraí Bibleagrafaíochta
Main Authors: Velu, Chinavenmeni S., Baktula, Avinash M., Grimes, H. Leighton
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Hematology 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680372/
https://ncbi.nlm.nih.gov/pubmed/19278956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-11-190215
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