MicroRNA profiling identifies miR-34a and miR-21 and their target genes JAG1 and WNT1 in the coordinate regulation of dendritic cell differentiation

MicroRNAs (miRNAs, miRs) modulate a multitude of cellular events. Here, we identify functional miRNA-protein networks that regulate human monocyte-derived dendritic cell (MDDC) differentiation. miRNA profiling revealed stage-specific differential expression of 20 miRNAs during days 1, 3, and 5 of MD...

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Bibliografiske detaljer
Main Authors: Hashimi, Sara T., Fulcher, Jennifer A., Chang, Margaret H., Gov, Lanny, Wang, Shuo, Lee, Benhur
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2009
Fag:
Phagocytes, Granulocytes, and Myelopoiesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927176/
https://ncbi.nlm.nih.gov/pubmed/19398721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-09-179150
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