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Ex vivo Inhibition of NF-κB Signaling in Alloreactive T-cells Prevents Graft-versus-host Disease
The ex vivo induction of alloantigen-specific hyporesponsiveness by costimulatory pathway blockade or exposure to immunoregulatory cytokines has been shown to inhibit proliferation, IL-2 production, and the GVHD capacity of adoptively transferred T-cells. We hypothesized that inhibition of the intra...
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| Asıl Yazarlar: | , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2680009/ https://ncbi.nlm.nih.gov/pubmed/19260829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2008.02533.x |
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