Ex vivo Inhibition of NF-κB Signaling in Alloreactive T-cells Prevents Graft-versus-host Disease

The ex vivo induction of alloantigen-specific hyporesponsiveness by costimulatory pathway blockade or exposure to immunoregulatory cytokines has been shown to inhibit proliferation, IL-2 production, and the GVHD capacity of adoptively transferred T-cells. We hypothesized that inhibition of the intra...

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Detalhes bibliográficos
Main Authors: O’Shaughnessy, M. J., Vogtenhuber, C., Sun, K., Sitcheran, R., Baldwin, A. S., Murphy, W. J., Dang, L., Jaffee, B., Palmer, E., Serody, J. S., Blazar, B. R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680009/
https://ncbi.nlm.nih.gov/pubmed/19260829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2008.02533.x
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