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ApoE-Dependent Modulation of HDL and Atherosclerosis by G2A in LDL Receptor-Deficient Mice Independent of Bone Marrow-Derived Cells

OBJECTIVE: Deletion of the lysophospholipid-sensitive receptor, G2A, in low-density lipoprotein receptor knockout (LDLR(-/-)) mice elevates plasma high-density lipoprotein (HDL) cholesterol and suppresses atherosclerosis. However, chemotactic action of G2A in monocytes/macrophages, in addition to it...

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Detalhes bibliográficos
Main Authors: Parks, Brian W., Srivastava, Roshni, Yu, Shaohua, Kabarowski, Janusz H.S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679811/
https://ncbi.nlm.nih.gov/pubmed/19164809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.108.179937
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