Loading...

Genotyping and inflated type I error rate in genome-wide association case/control studies

BACKGROUND: One common goal of a case/control genome wide association study (GWAS) is to find SNPs associated with a disease. Traditionally, the first step in such studies is to assign a genotype to each SNP in each subject, based on a statistic summarizing fluorescence measurements. When the distri...

Full description

Saved in:
Bibliographic Details
Main Authors: Sampson, Joshua N, Zhao, Hongyu
Format: Artigo
Language:Inglês
Published: BioMed Central 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679732/
https://ncbi.nlm.nih.gov/pubmed/19236714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-68
Tags: Add Tag
No Tags, Be the first to tag this record!